Medicinal Chemistry

Charnwood Molecular can offer medicinal chemistry support to the pharmaceutical and biotechnology industries. Our medicinal chemists have experience of working in various therapeutic areas including oncology, obesity, immunology and the treatment of cardiovascular diseases.

Our services include:

Lead Discovery

  • Synthesis of reference compounds for validation of screens and analogues of these.
  • Synthesis of analogues of natural ligands
  • Synthesis of de novo designed compounds
  • Synthesis of analogues of a hit from high throughput screening

Lead Optimisation

  • Synthesis of analogues around a lead compound
  • Parallel synthesis of analogues
  • Bioisosteric replacement
  • Patent exemplification
  • Improvement of physical properties

Contact us to discuss your requirements

 

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