Our team has worked in pre-clinical discovery, designing and developing low, medium and high throughput assays in both cellular and non-cellular assay formats.

Therefore, we have experience of a wide range of technologies designed to prosecute these activities in a scalable manner whilst bringing to bear technological developments that have the ability to probe ever further into the molecular interactions from which the drugs of the future may be identified.

Whatever your therapeutic area or target class we are able to apply our expertise to your project.

We work across the drug discovery pipeline, from target identification, validation and hit to lead, through to lead identification and optimisation.

At Charnwood Molecular , we have significant experience of different target classes and use cutting edge technologies to deliver client projects in a timely, efficient and cost-effective manner.

We can offer standalone biology-based project support through to a fully integrated approach to drug discovery and development, incorporating our services in medicinal and process research chemistry.

Our leadership has decades of large pharma experience in drug discovery gained in companies including Hoffmann La Roche, Smith Kline Beecham, GlaxoWellcome, AstraZeneca, ICI and UCB.

Find out more about our scientific team.

Capabilities

• High throughput screening
• Cell based screening
• Phenotypic screening
• Cell culture services
• Biochemical screening
• Instrument & reagent validation
• SPR
• Liquid handling

Specialised technologies

• Fluorescence and luminescence based assays (both cell and non-cell based)
• FLIPR screening
• Label-free screening
• High content screening
• JESS: Western blot assay system
• Quantitative PCR
• 3D cell biology
• Flow cytometry
• Incucyte based kinetic imaging

We have expertise in a variety of target classes including:

• Kinases
• GPCRs
• Ion channels
• PROTACs
• PPIs

Therapeutic areas covered include:

• Oncology
• Inflammation and immunology
• Central nervous system
• Metabolic diseases
• Respiratory diseases
• Infectious diseases
• Rare/orphan diseases