Central nervous system
Neuroscience involves the study and development of drugs to address a range of diseases affecting the central nervous system (CNS). These include everything from headaches, epilepsy, seizures and stroke through to Alzheimer’s, dementia, Parkinson’s and other neurological conditions.
The challenge of CNS
Without doubt the development of drugs for CNS is one of the most challenging areas of drug discovery.
Latest developments in neuroscientific research mean that the identification of small molecular compounds can eventually become new drugs . We have specific expertise in developing small molecule compounds for GPCR targets.
Integrated drug discovery approach
At Charnwood Molecular our integrated drug discovery approach, bringing together expertise from our various in-house teams, including DMPK, bioscience and medicinal chemistry, means that we are able to provide an integrated drug discovery solution for clients looking to develop a range of neurological medicinal solutions.
Our teams are experienced at working in highly challenging environments and maintain the highest standards in managing associated risks.
Assays available to support CNS projects include:
- Neurite outgrowth
- Ion channel – flux & membrane potential
- GPCR signaling
- High content imaging
- Western blot and qPCR
Our track record
Take a look at an example of our work in this area with the following case study:
Download our eBook on developing effective assays: